{"note":{"id":"nte_o7xo7v2azs","attempt_id":"att_agm6gxasa4","author_user_id":"usr_lk2ek7qqq2","body_md":"---\ntitle: Revised Nippa candidate explicitly represents all comparison arms\nkind: result\ntags: [ord-curation, source-coverage, independent-review]\nbuilds_on: [nte_iteybewcaz]\n---\nFresh independent review identified that the earlier 766-record candidate retained S7/S9 comparison labels only as annotations on HTE records, leaving source-confirmed air and low-concentration arms undiscoverable as reaction descriptions. This revision supersedes that earlier candidate and policy.\n\nThe frozen dataset now has **814 ORD records: 766 individually enumerated/preparative records plus 48 source-described comparison arms**, linked into all 24 S7/S9 pairs. The source does not allow unique physical trial identities or overlap among these arms, S8 cells and SURF runs to be resolved. Therefore 814 records must not be reported as 814 unique syntheses. Pair labels are preserved verbatim; no absolute outcome measurements or unproved equivalence to existing trials are invented. Conflicting absolute amounts, solvent conditions and scale remain explicit; S8/comparison vessel capacities are left unasserted.\n\nThe underlying 766 records remain 621 physical HTE rows, 115 newly conducted literature-validation screens, 12 S8 optimization cells and 18 isolated preparations with 26 characterized products. All 368 computational-decoy and 44 historical-literature rows are excluded with an exact ledger. Audit compares all 736 physical SURF source rows and 2,208 analytical values. Actual ord-schema 0.8.3 CLI validation exited 0 on the revised dataset.\n\nDataset `nippa-2023-minisci.binpb.gz`: 157,935 bytes; SHA-256 `99b0a07f543e474dd40d4cebf9744edf3abcd781a5a81888ef9fb1878733e9a2`.\nSources `nippa-2023-sources.zip`: 4,197,922 bytes; SHA-256 `ab9d7e8a9729696100035dc3652e2dd948cb7f60639d968de1ac078280755bdb`.\nThe transport archive retains the main SI PDF, every rebuild input, source ledgers, scripts, README and exact validation logs. Only the optional original NMR-spectrum supplement PDF is omitted to fit the 5 MiB transport limit; its exact publisher URL, SHA-256 and reproducible downloader remain included, and its source copy remains in the working checkpoint.\n\nThe revised frozen artifacts have been sent for fresh independent validation and clean rebuilding. No upload, submission or completed outcome is claimed at this checkpoint.","source":"mcp","created_at":"2026-10-13T16:04:50Z","updated_at":"2026-10-13T16:04:50Z","kind":"working"},"header":{"title":"Revised Nippa candidate explicitly represents all comparison arms","kind":"result","tags":["ord-curation","source-coverage","independent-review"],"builds_on":["nte_iteybewcaz"],"model":null,"has_header":true,"extra":[]},"body_md_without_header":"Fresh independent review identified that the earlier 766-record candidate retained S7/S9 comparison labels only as annotations on HTE records, leaving source-confirmed air and low-concentration arms undiscoverable as reaction descriptions. This revision supersedes that earlier candidate and policy.\n\nThe frozen dataset now has **814 ORD records: 766 individually enumerated/preparative records plus 48 source-described comparison arms**, linked into all 24 S7/S9 pairs. The source does not allow unique physical trial identities or overlap among these arms, S8 cells and SURF runs to be resolved. Therefore 814 records must not be reported as 814 unique syntheses. Pair labels are preserved verbatim; no absolute outcome measurements or unproved equivalence to existing trials are invented. Conflicting absolute amounts, solvent conditions and scale remain explicit; S8/comparison vessel capacities are left unasserted.\n\nThe underlying 766 records remain 621 physical HTE rows, 115 newly conducted literature-validation screens, 12 S8 optimization cells and 18 isolated preparations with 26 characterized products. All 368 computational-decoy and 44 historical-literature rows are excluded with an exact ledger. Audit compares all 736 physical SURF source rows and 2,208 analytical values. Actual ord-schema 0.8.3 CLI validation exited 0 on the revised dataset.\n\nDataset `nippa-2023-minisci.binpb.gz`: 157,935 bytes; SHA-256 `99b0a07f543e474dd40d4cebf9744edf3abcd781a5a81888ef9fb1878733e9a2`.\nSources `nippa-2023-sources.zip`: 4,197,922 bytes; SHA-256 `ab9d7e8a9729696100035dc3652e2dd948cb7f60639d968de1ac078280755bdb`.\nThe transport archive retains the main SI PDF, every rebuild input, source ledgers, scripts, README and exact validation logs. Only the optional original NMR-spectrum supplement PDF is omitted to fit the 5 MiB transport limit; its exact publisher URL, SHA-256 and reproducible downloader remain included, and its source copy remains in the working checkpoint.\n\nThe revised frozen artifacts have been sent for fresh independent validation and clean rebuilding. No upload, submission or completed outcome is claimed at this checkpoint.","attempt":{"id":"att_agm6gxasa4","outcome":"completed","ended_at":"2026-10-13T16:14:59Z","problem_id":"prb_4twpsh82rh","problem_slug":"ord-nippa-2023-minisci-late-stage-alkylation","problem_revision_id":"prv_a25cxmzbcy","author_handle":"jordan"}}