{
  "source": "ORD Dataset Wishlist",
  "snapshot_date": "2026-09-25",
  "ord_wishlist_status_at_snapshot": "Available",
  "ord_wishlist_card": "https://github.com/orgs/open-reaction-database/projects/11?pane=issue&itemId=126570022",
  "ord_data_issue": null,
  "title": "Alkene-Coordinated Palladium(0) Cross-Coupling Precatalysts: Comparing Oxidative Addition and Catalytic Reactivity for Dimethyl Fumarate and Maleic Anhydride Stabilizing Ligands",
  "doi": "10.26434/chemrxiv-2024-g4vxk",
  "journal": "ChemRxiv",
  "publication_date": "2024-02-02",
  "authors": [
    "Gilian T. Thomas",
    "Jared Z. Litman",
    "Binh Dang Ho",
    "Jingjun Huang",
    "Kalina Blonska",
    "Nathan D. Schley",
    "David C. Leitch"
  ],
  "article_open_access": {
    "status": "green",
    "license": "cc-by-nc-nd"
  },
  "dataset_size_estimate": 72,
  "experiment_type": "MTE",
  "ord_priority": null,
  "ord_difficulty": null,
  "source_data_kind": "plate_images_or_heatmaps",
  "smiles_in_source": "no",
  "needs_author_contact": false,
  "data_locations": [
    {
      "url": "https://doi.org/10.26434/chemrxiv-2024-g4vxk",
      "what": "ChemRxiv preprint and SI; catalytic comparisons shown as 24-well array images (per ORD notes)",
      "license": "CC BY-NC-ND 4.0 (preprint, per Crossref)"
    },
    {
      "url": "https://doi.org/10.1021/acs.organomet.4c00065",
      "what": "Published version (Organometallics 2024) and its SI",
      "license": "ACS standard terms (closed)"
    }
  ],
  "notes": "Source: Thomas et al., ChemRxiv 2024, doi:10.26434/chemrxiv-2024-g4vxk, published as Organometallics 2024, doi:10.1021/acs.organomet.4c00065. About 72 reactions: catalytic comparisons of the air-stable DAB-Pd-DMFU (dimethyl fumarate) precatalyst, and phosphine-Pd-DMFU complexes formed in situ, against other Pd sources in Heck coupling, Suzuki-Miyaura coupling and Miyaura borylation. The data is presented as several 24-well array images. Read each well's conditions and outcome from the figures and cross-check against the SI experimental section. Structures are not provided as SMILES and must be drawn from the reaction schemes. Cite the paper DOI; the preprint is CC BY-NC-ND 4.0.",
  "verification_caveats": "Values are transcribed from images, so the reviewer must spot-check wells against the figures. Several reaction templates (Heck, Suzuki, borylation) may sit in one dataset. Precatalysts formed in situ (Pd source plus ligand) must be represented as separate inputs. Outcomes are likely assay yields or conversions from HTE analysis."
}