{
  "source": "ORD Dataset Wishlist",
  "snapshot_date": "2026-09-25",
  "ord_wishlist_status_at_snapshot": "Available",
  "ord_wishlist_card": "https://github.com/orgs/open-reaction-database/projects/11?pane=issue&itemId=126570065",
  "ord_data_issue": null,
  "title": "Unlocking the Potential of High-Throughput Experimentation for Electrochemistry with a Standardized Microscale Reactor",
  "doi": "10.1021/acscentsci.1c00328",
  "journal": "ACS  Central Sci",
  "publication_date": "2021-08-05",
  "authors": [
    "Jonas Rein",
    "James R. Annand",
    "Michael K. Wismer",
    "Jiantao Fu",
    "Juno C. Siu",
    "Artis Klapars",
    "Neil A. Strotman",
    "Dipannita Kalyani",
    "Dan Lehnherr",
    "Song Lin"
  ],
  "article_open_access": {
    "status": "diamond",
    "license": "cc-by-nc-nd"
  },
  "dataset_size_estimate": 240,
  "experiment_type": "HTE electrochemistry",
  "ord_priority": "Medium",
  "ord_difficulty": "Hard",
  "source_data_kind": "plate_images_or_heatmaps",
  "smiles_in_source": "no",
  "needs_author_contact": false,
  "data_locations": [
    {
      "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC8393209/",
      "what": "PMC full text (Europe PMC XML fetched). SI files: oc1c00328_si_001.pdf (procedures, analysis, characterization; holds the plate images), si_002.zip (technical drawings and CAD files for the reactor), si_003.xls (bill of materials, not reaction data), si_004.mp4 (setup video).",
      "license": "CC-BY-NC-ND-4.0"
    },
    {
      "url": "https://doi.org/10.1021/acscentsci.1c00328",
      "what": "ACS Central Science 2021 article landing page. Not fetched because ACS blocks bots. ChemRxiv preprints exist (10.26434/chemrxiv.14173538 v1 and v2).",
      "license": "CC-BY-NC-ND-4.0"
    }
  ],
  "notes": "Source: ACS Cent. Sci. 2021, 10.1021/acscentsci.1c00328 (open access, CC BY-NC-ND 4.0; also PMC8393209). The HTE electrochemistry data (about 240 reactions over 10 plates) is only shown as plate images in the SI PDF. The images must be transcribed into a table and linked to the reaction conditions. The SI XLS file is a bill of materials for the reactor, not reaction data. The ZIP holds CAD files. Record electrochemistry details (constant current or constant voltage mode, current or voltage, electrode materials, cell setup) in ORD electrochemistry conditions. Source files carry a no-derivatives, non-commercial license, so treat them as reference only.",
  "verification_caveats": "Values are read from images, so transcription errors are likely. Readable per-well numbers could not be confirmed without opening the SI PDF. Outcomes are probably assay yields or LCAP, not isolated yields. Electrochemical parameters must be encoded properly. The 10 plates may span several reaction classes and need consistent reactant/product SMILES per plate."
}