{
  "source": "ORD Dataset Wishlist",
  "snapshot_date": "2026-09-25",
  "ord_wishlist_status_at_snapshot": "Available",
  "ord_wishlist_card": "https://github.com/orgs/open-reaction-database/projects/11?pane=issue&itemId=126569948",
  "ord_data_issue": null,
  "title": "High Throughput Multidimensional Kinetic Screening in Continuous Flow Reactors",
  "doi": "10.1002/anie.202308838",
  "journal": "ACIE",
  "publication_date": "2023-08-03",
  "authors": [
    "Bo Zhang",
    "Ansila Mathoor",
    "Tanja Junkers"
  ],
  "article_open_access": {
    "status": "hybrid",
    "license": "other-oa"
  },
  "dataset_size_estimate": null,
  "experiment_type": "transient flow",
  "ord_priority": null,
  "ord_difficulty": null,
  "source_data_kind": "author_request_needed",
  "smiles_in_source": "no",
  "needs_author_contact": true,
  "data_locations": [
    {
      "url": "https://doi.org/10.1002/anie.202308838",
      "what": "Angew. Chem. article and Wiley SI (SI references a separate raw-data Excel file that could not be located)",
      "license": "Article CC-BY-NC-ND 4.0 per Crossref (OpenAlex lists other-oa); SI/Excel license unknown"
    },
    {
      "url": "https://api.datacite.org/dois?query=Junkers",
      "what": "figshare and DataCite search for a deposited raw-data file; none found",
      "license": "n/a"
    }
  ],
  "notes": "Source: Zhang, Mathoor and Junkers, Angew. Chem. Int. Ed. 2023, doi:10.1002/anie.202308838 (open access; Crossref lists CC-BY-NC-ND 4.0 for the article). This is high-throughput multidimensional kinetic screening of polymerizations in continuous-flow reactors using transient-flow operation, a custom reactor layout and a custom controller. The SI states that all raw data for monomer concentration, degree of polymerization (DP) and residence-time screening are in a separate Excel file. That file could not be found on the publisher site, and no public repository deposit was located, so it likely has to be obtained from the authors. Pitfalls: polymer products must be described (target DP, conversion, molecular weight/dispersity rather than a single product SMILES). Transient-flow experiments produce continuous kinetic profiles that must be discretized into ORD reactions or time-course measurements. The custom reactor setup needs a careful flow description.",
  "verification_caveats": "Transient flow (conditions ramped over time; kinetic time courses). Polymer products (no discrete product SMILES; DP/Mn/dispersity outcomes). Custom reactor and controller setup. Raw data file not located."
}