{
  "source": "ORD Dataset Wishlist",
  "snapshot_date": "2026-09-25",
  "ord_wishlist_status_at_snapshot": "Available",
  "ord_wishlist_card": "https://github.com/orgs/open-reaction-database/projects/11?pane=issue&itemId=126964663",
  "ord_data_issue": null,
  "title": "High-throughput optimization of the C–H arylation of oxetanes via Ni/aldehyde photocatalysis",
  "doi": "10.1039/D4OB01271B",
  "journal": "Org Biomol Chem",
  "publication_date": "2024-09-05",
  "authors": [
    "Justin B. Diccianni",
    "Bo Nan Hao",
    "Wei Liu",
    "Iulia I. Strambeanu"
  ],
  "article_open_access": {
    "status": "closed",
    "license": null
  },
  "dataset_size_estimate": 500,
  "experiment_type": "HTE",
  "ord_priority": "High",
  "ord_difficulty": "Hard",
  "source_data_kind": "si_pdf_tables",
  "smiles_in_source": "no",
  "needs_author_contact": false,
  "data_locations": [
    {
      "url": "https://pubs.rsc.org/en/content/articlelanding/2024/ob/d4ob01271b",
      "what": "Article landing page with the ESI PDF containing HTE tables (returned 403 to automated fetch)",
      "license": "Closed article; Crossref lists RSC terms of use for the AM after a 613-day embargo; SI license unknown"
    }
  ],
  "notes": "HTE optimization of oxetane C-H arylation via Ni/aldehyde photocatalysis (Org. Biomol. Chem. 2024). ORD reports the reaction data as tables in the ESI PDF, about 500 reactions. Compound SMILES are not provided and must be derived from structures and names in the paper and ESI. Photochemical conditions (light source, wavelength, intensity, vessel/plate geometry) must be captured from the experimental section. The article is not open access; the ESI is usually freely downloadable from the RSC article page, but this was not verified. Cite DOI 10.1039/D4OB01271B.",
  "verification_caveats": "Photochemical HTE needs illumination metadata. Outcomes may be assay yields or LCMS/UPLC ratios; confirm the analytical method. PDF table extraction and manual SMILES generation are needed."
}