{
  "source": "ORD Dataset Wishlist",
  "snapshot_date": "2026-09-25",
  "ord_wishlist_status_at_snapshot": "Available",
  "ord_wishlist_card": "https://github.com/orgs/open-reaction-database/projects/11?pane=issue&itemId=126846959",
  "ord_data_issue": null,
  "title": "Development of a General Method for the Hiyama–Denmark Cross-Coupling of Tetrasubstituted Vinyl Silanes",
  "doi": "10.1021/acscatal.2c03981",
  "journal": "ACS Catalysis",
  "publication_date": "2022-10-12",
  "authors": [
    "Sarah B. Pawley",
    "Allyssa M. Conner",
    "Humair M. Omer",
    "Donald A. Watson"
  ],
  "article_open_access": {
    "status": "green",
    "license": null
  },
  "dataset_size_estimate": 96,
  "experiment_type": "HTE",
  "ord_priority": "High",
  "ord_difficulty": "Hard",
  "source_data_kind": "author_request_needed",
  "smiles_in_source": "no",
  "needs_author_contact": true,
  "data_locations": [
    {
      "url": "https://doi.org/10.1021/acscatal.2c03981",
      "what": "Article landing page (ACS Catalysis)",
      "license": "unknown; OpenAlex green OA via PMC author manuscript (article, not data)"
    },
    {
      "url": "https://acs.figshare.com/articles/journal_contribution/21320890",
      "what": "SI PDF cs2c03981_si_001.pdf (15.9 MB): tables and pie charts per curator notes. Listing only, not downloaded.",
      "license": "CC BY-NC 4.0 (figshare label)"
    },
    {
      "url": "https://acs.figshare.com/articles/dataset/21320893",
      "what": "SI zip cs2c03981_si_002.zip (99 MB). Its central-directory listing shows only Bruker NMR raw data (Products/ and Starting Materials/ FID folders) and no spreadsheets.",
      "license": "CC BY-NC 4.0 (figshare label)"
    },
    {
      "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933925",
      "what": "PMC author manuscript",
      "license": "unknown"
    }
  ],
  "notes": "Hiyama–Denmark cross-coupling of tetrasubstituted vinyl silanes (University of Delaware), ACS Catalysis 2022, DOI 10.1021/acscatal.2c03981. HTE ligand-screen results (about 96 reactions) appear in the SI PDF as tables and pie-chart images. The 99 MB SI zip holds only raw NMR FID data for isolated compounds, not screening data. The 96 ligands need identities and SMILES that the SI does not give in machine-readable form. An author-supplied screening table with ligand identities is needed before curation.",
  "verification_caveats": "Ligand identities are the main gap. Pie-chart outcomes are qualitative or binned unless raw values are supplied. The isolated-yield scope table could be curated separately, but that is not the HTE data."
}