{
  "source": "ORD Dataset Wishlist",
  "snapshot_date": "2026-09-25",
  "ord_wishlist_status_at_snapshot": "Available",
  "ord_wishlist_card": "https://github.com/orgs/open-reaction-database/projects/11?pane=issue&itemId=127178740",
  "ord_data_issue": null,
  "title": "Exploring New Reactions with an Accessible High-throughput Screening (Open-HTS) Chemical Robotic System",
  "doi": "10.1021/acs.oprd.5c00027",
  "journal": "OPRD",
  "publication_date": "2025-05-28",
  "authors": [
    "Heming Jiang",
    "Ying Chen",
    "Meirong Huang",
    "Tingjun Liu",
    "Yun‐Dong Wu",
    "Xinhao Zhang"
  ],
  "article_open_access": {
    "status": "closed",
    "license": null
  },
  "dataset_size_estimate": 3920,
  "experiment_type": "HTE photo flow",
  "ord_priority": "High",
  "ord_difficulty": "Hard",
  "source_data_kind": "plate_images_or_heatmaps",
  "smiles_in_source": "no",
  "needs_author_contact": true,
  "data_locations": [
    {
      "url": "https://doi.org/10.1021/acs.oprd.5c00027",
      "what": "Article landing page (OPRD) with the result image grid",
      "license": "closed (OpenAlex); ACS TDM policy per Crossref"
    },
    {
      "url": "https://acs.figshare.com/articles/journal_contribution/29175858",
      "what": "SI PDF op5c00027_si_001.pdf (17.4 MB). Listing only, not downloaded.",
      "license": "CC BY-NC 4.0 (figshare label)"
    },
    {
      "url": "https://acs.figshare.com/articles/media/29175861",
      "what": "SI videos op5c00027_si_002.mp4 and si_003.mp4 (record 29175864) of the robotic system. Not reaction data.",
      "license": "CC BY-NC 4.0 (figshare label)"
    }
  ],
  "notes": "Open-HTS accessible robotic high-throughput screening, including photo/flow reactions (Peking University / Shenzhen Bay Laboratory), OPRD 2025, DOI 10.1021/acs.oprd.5c00027 (closed article). Results for about 3920 reactions appear in the paper as an image grid, with 83 hits, and the primary readout is qualitative (whether the product ion was detected by MS). The SI on ACS figshare is a 17 MB PDF plus two videos. No machine-readable data file or public code repository was found. A spreadsheet of the screen (components per well and detection result) is needed before curation.",
  "verification_caveats": "Outcomes are qualitative (product ion detected yes or no), with no yields. Products are mostly not isolated or characterized. Reading about 3920 wells from an image is error-prone, and component SMILES must be generated."
}