{
  "source": "ORD Dataset Wishlist",
  "snapshot_date": "2026-09-25",
  "ord_wishlist_status_at_snapshot": "Available",
  "ord_wishlist_card": "https://github.com/orgs/open-reaction-database/projects/11?pane=issue&itemId=128979768",
  "ord_data_issue": null,
  "title": "Stereodivergent Construction of Decalin-Based Terpenoids",
  "doi": "10.26434/chemrxiv-2025-8r6bx",
  "journal": "ChemRxiv",
  "publication_date": "2025-09-11",
  "authors": [
    "Samantha L. Barlock",
    "Alexander S. Shved",
    "Kayla D. Landers",
    "Binh Khanh Mai",
    "Shogo Fujiki",
    "Wayne Lo",
    "Peter C. Ryffel",
    "Andrew G. Feng",
    "Viet D. Nguyen",
    "David A. Petrone",
    "Scott E. Denmark",
    "David Šarlah"
  ],
  "article_open_access": {
    "status": "green",
    "license": "cc-by-nc-nd"
  },
  "dataset_size_estimate": 200,
  "experiment_type": "small HTE",
  "ord_priority": "Medium",
  "ord_difficulty": "Hard",
  "source_data_kind": "si_pdf_tables",
  "smiles_in_source": "no",
  "needs_author_contact": false,
  "data_locations": [
    {
      "url": "https://doi.org/10.26434/chemrxiv-2025-8r6bx",
      "what": "ChemRxiv preprint (2025-09-11) with the SI HTE tables named on the ORD card. The ChemRxiv API sat behind a Cloudflare challenge (403), so the SI file list was not inspected; only the Crossref metadata was read.",
      "license": "CC-BY-NC-ND-4.0 (preprint, per Crossref)"
    },
    {
      "url": "https://doi.org/10.1021/jacs.6c01881",
      "what": "Version of record, JACS 2026, titled 'Stereodivergent Construction of trans-Decalin-Based Terpenoids'. Crossref lists two SI PDF components, ja6c01881_si_001.pdf and ja6c01881_si_002.pdf. Their contents were not inspected.",
      "license": "ACS standard terms (Crossref TDM/VOR policies); not open"
    }
  ],
  "notes": "Source: the SI of the ChemRxiv preprint 10.26434/chemrxiv-2025-8r6bx. The paper is now published as JACS 10.1021/jacs.6c01881 (2026), which has two SI PDFs. The HTE results (about 200 reactions) are in PDF tables. About 70 ligands appear only as drawings or labels and must be converted to structures with correct stereochemistry. The preprint and the JACS version differ in title and author list. Reconcile any differences in the data and cite the version of record (optionally also the preprint). The preprint is CC BY-NC-ND 4.0 and the JACS SI is under ACS terms, so treat the source files as reference only.",
  "verification_caveats": "Stereodivergent chemistry: outcomes probably include diastereo- and enantioselectivity, which need correct ORD encoding. About 70 ligands need stereo-correct SMILES taken from drawings. Numbers may differ between the preprint and JACS SI tables. The table layout must be converted into per-reaction records."
}