{
  "source": "ORD Dataset Wishlist",
  "snapshot_date": "2026-09-25",
  "ord_wishlist_status_at_snapshot": "Available",
  "ord_wishlist_card": "https://github.com/orgs/open-reaction-database/projects/11?pane=issue&itemId=127186699",
  "ord_data_issue": null,
  "title": "General Method for Ni-Catalyzed C–N Cross-Couplings of (Hetero)Aryl Chlorides with Anilines and Aliphatic Amines under Homogeneous Conditions Using a Dual-Base Strategy",
  "doi": "10.1021/acs.organomet.3c00419",
  "journal": "Organometallics",
  "publication_date": "2023-11-01",
  "authors": [
    "Roberto Silva Villatoro",
    "Joshua R. Belfield",
    "Hadi D. Arman",
    "Lucas W. Hernandez",
    "Eric M. Simmons",
    "Zachary J. Garlets",
    "Steven R. Wisniewski",
    "John R. Coombs",
    "Doug E. Frantz"
  ],
  "article_open_access": {
    "status": "closed",
    "license": null
  },
  "dataset_size_estimate": 400,
  "experiment_type": "HTE",
  "ord_priority": "High",
  "ord_difficulty": "Hard",
  "source_data_kind": "author_request_needed",
  "smiles_in_source": "no",
  "needs_author_contact": true,
  "data_locations": [
    {
      "url": "https://acs.figshare.com/articles/journal_contribution/General_Method_for_Ni-Catalyzed_C_N_Cross-Couplings_of_Hetero_Aryl_Chlorides_with_Anilines_and_Aliphatic_Amines_under_Homogeneous_Conditions_Using_a_Dual-Base_Strategy/24476269",
      "what": "ACS SI mirror: om3c00419_si_001.pdf (8.2 MB; listed, not downloaded)",
      "license": "CC BY-NC 4.0 (figshare record)"
    },
    {
      "url": "https://doi.org/10.1021/acs.organomet.3c00419",
      "what": "Article (Organometallics 2023); closed access",
      "license": "closed (OpenAlex)"
    }
  ],
  "notes": "Ni-catalyzed C-N cross-coupling HTE (dual-base strategy), about 400 reactions. The full reaction data exists as a multi-sheet spreadsheet (about 15 sheets) from the originating company and is not publicly available. The public SI is a PDF (ACS, mirrored on figshare, CC BY-NC 4.0). The sheets may need different ORD templates, and compounds are listed without SMILES, so SMILES generation is required. This item is currently assigned within ORD.",
  "verification_caveats": "Multiple sheets likely correspond to different experiment designs and templates. Compound list requires SMILES generation. Source data is private."
}