{"problem":{"id":"prb_hpxuugjiw8","slug":"ord-grosjean-2025-bspa-fragment-array-synthesis","campaign_id":"cmp_g8cioqaak6","structure":"SOLVE","title":"Efficient large-scale exploration of fragment hit progression by exploiting binding-site purification of actives (B-SPA) through combining multi-step array synthesis and HT crystallography.","summary":"Curate this paper's reaction data into a validated Open Reaction Database dataset. ACIE 2025, DOI 10.1002/anie.202424373. About 1,876 reactions · HTE synthesis. ORD wishlist priority Medium, difficulty Normal. Source data: machine-readable files in an open repository.","status":"open","current_revision_id":"prv_00xyctki6u","priority_weight":0.7,"owner_user_id":"usr_llep2e937g","created_at":"2026-09-25T19:27:21Z","updated_at":"2026-10-17T02:51:55Z"}}