Deconvoluting Low Yield from Weak Potency in Direct-to-Biology Workflows with Machine Learning

Checks run in this order. Open a step to inspect its rules, checker or review rubric.

1. Curation reviewReviewReview required

   A reviewer with ORD curation experience compares the dataset with the paper: coverage, structures, amounts, conditions, outcomes and provenance, and checks the validator output in the sources archive.

   Eligible reviewers must complete the pinned rubric. Seat availability and completion are not guaranteed.

   Read the pinned rubric and reviewer rules

   ORD curation review: one campaign reviewer · pinned protocol

   ORD curation reviewer · 1 reviewer

   Compare the dataset with the paper named in card (its tables and Supporting Information), using the sources archive to see how it was built. Pass only if you would accept it into ORD after at most cosmetic fixes. Check: validation.txt in the sources archive shows ORD's validator (ord-schema 0.8.3) passing this exact dataset file with no errors (re-run it if in doubt); every reaction in the stated scope is present and none is invented; every SMILES matches the compound the paper names (enumeration mix-ups, one abbreviation mapped to two structures, a similar compound substituted); amounts, reaction roles, conditions and workups (internal standards belong in the workup); outcomes (is_desired_product, yields within 0-100% with an analysis); provenance (the paper's DOI, a real curator name and email); a meaningful dataset name and description. List every defect you find, with where it is.

   Rationale requiredAt least 1 citationConfidence required

   Response fields and full schema

   • coverage · required "complete" / "partial" / "insufficient"
     How much of the paper's in-scope reaction data the dataset captures.
   • defects · required array
   • verdict · required "pass" / "fail" / "uncertain"

   {
     "additionalProperties": false,
     "properties": {
       "coverage": {
         "description": "How much of the paper's in-scope reaction data the dataset captures.",
         "enum": [
           "complete",
           "partial",
           "insufficient"
         ]
       },
       "defects": {
         "items": {
           "additionalProperties": false,
           "properties": {
             "severity": {
               "enum": [
                 "must_fix",
                 "should_fix",
                 "note"
               ]
             },
             "what": {
               "maxLength": 1000,
               "type": "string"
             },
             "where": {
               "maxLength": 300,
               "type": "string"
             }
           },
           "required": [
             "severity",
             "where",
             "what"
           ],
           "type": "object"
         },
         "maxItems": 200,
         "type": "array"
       },
       "verdict": {
         "enum": [
           "pass",
           "fail",
           "uncertain"
         ]
       }
     },
     "required": [
       "verdict",
       "coverage",
       "defects"
     ],
     "type": "object"
   }

   Only designated Campaign reviewers may claim a seat.The submitter is excluded.Responses on this node are withheld until it completes.Declare any agent assistance used; a declaration is optional under this protocol.

   Exact reviewer eligibility, visibility and Skill pins

   {
     "reviewers": {
       "allowed": null,
       "assistance": {
         "allowed": [],
         "required": false
       },
       "count": 1,
       "eligibility": {
         "organization_id": null,
         "rule": "campaign_reviewers",
         "user_ids": null
       },
       "independent": true,
       "kind": "human"
     },
     "conflicts": {
       "exclude_submitter": true,
       "exclude_submitter_organization": false
     },
     "visibility": {
       "hidden": [
         "submitter_identity",
         "submitter_organization"
       ],
       "prior_nodes": [],
       "stage_evidence": true
     },
     "skills": [
       {
         "requirement": "required",
         "skill_version_id": "skv_k5sivlohu1"
       }
     ]
   }

   How judgments become the outcome

   Decide

   Accept when at least 1 responses have verdict equals "pass". Reject when at least 1 have verdict equals "fail". Otherwise unresolved.

   Inputs, in order: curator · decision

   Final outcome comes from decision. Accept passes this stage; reject refutes it; unresolved is inconclusive. All verification stages must pass.

   Node deadline: 336 hoursClaim hold: 1440 minutes, bounded by the node deadline

   Protocol identity and full rules

   rpt_mumofu1g8r
sha256:b603bab4f3d212cc983c1ec2ba54252a4b34cf47fe3362387f1e5783b8daaa8d

   Read the complete pinned protocol →

   {
     "output": "decision",
     "policy": {
       "assignment_timeout_hours": 336,
       "claim_hold_minutes": 1440
     }
   }