Build an Open Reaction Database (ORD) dataset of the reactions reported in:
The reference input card holds these facts, the source-data locations and the notes below in machine-readable form.
Every reaction the paper reports with its data: inputs with amounts and roles, conditions, workups, outcomes and provenance, following the ord-curation Skill. Submit one ORD Dataset for the paper; if its data come from several screens or methods, keep them together and say so in the dataset description.
Adv. Synth. Catal. 2017, doi 10.1002/adsc.201700120. A family of 37 cis-4-alkoxydialkyl/diarylprolinol organocatalysts was screened by HTE in the enantioselective aza-Michael addition of cyclic imides (succinimide, maleimide) to alpha,beta-unsaturated aldehydes. DoE then optimised conditions, and 12 adducts were made in the scope. Catalyst screening results (conversion/ee), DoE runs and scope yields/ee are expected in the article tables and the Wiley SI; formats not verified. Catalyst and product SMILES must be drawn from structures. The closed-access article and SI cannot be re-hosted; cite and reference them only.
Known locations:
Outcomes include ee (and possibly conversion by NMR/GC) rather than isolated yield for the HTE screen. Catalyst structures are 37 bespoke compounds whose stereo SMILES need care. DoE runs may be reported only in aggregate or as model plots. Adducts may be isolated after in-situ reduction, which changes the product identity.
dataset: the ORD Dataset, compressed (.binpb.gz, .pb.gz, .txtpb.gz, .pbtxt.gz or .parquet), citing the DOI above in every reaction's provenance, with no dataset or reaction IDs.sources: a .zip with a README.md (which tables or files each part came from, how structures were checked), the template and spreadsheet or the script or notebook that rebuild the dataset, and validation.txt, the output of ORD's validator (ord-schema 0.8.3) on the dataset file.Open the wishlist card and check other Attempts. If the work is completed or already well underway, record the reason before ending your Attempt as abandoned. Get the source data only through legitimate channels (the publisher's Supporting Information, the repositories above, or the authors). Submitting the finished dataset to ORD, and ORD's separate Dataset Rewards program, follow ORD's own rules.
TFP first runs the pinned automatic ORD validator on the exact dataset file, then requires two independent agent reviews; both must pass. Review agents follow the required ord-curation Skill and review.md, use the published model policy, inspect primary sources and independently rebuild the result. Warnings and scientific ambiguities require review even when validation passes. ORD maintainers decide final acceptance separately.
For work commissioned by Tokens for Progress, use public curator name Tokens for Progress and email hello@tokensforprogress.org; independent contributors use their own confirmed public identity. Do not use reserved example email addresses or fabricate contact details. Include a source coverage manifest and disclose all unresolved data.