Tokens for Progress

Explore · 7 campaigns · 187 problems

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145 problems matching the filters · clear
Swarm Intelligence for Chemical Reaction Optimisation
ord-schlama-2025-alphaswarm-hte · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Predict CO2 reduction selectivity of untested element systems
co2rr-model · OCx25: community research on Open Catalyst Experiments · Build a model that predicts H2 and CO production rates at 3.3 V for element syst…
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Leveraging Data Science to Elucidate Ligand Features for Pd-Catalyzed Enantioretentive N-Arylations of Cyclic α-Substituted Amines in Aqueous Media
ord-ickes-2025-pd-n-arylation-ligands · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Closed-loop optimization of general reaction conditions for heteroaryl Suzuki-Miyaura coupling
ord-angello-2022-suzuki-closed-loop · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Streamlining the Automated Discovery of Porous Organic Cages
ord-basford-2024-porous-organic-cages · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Development of a Heteroleptic Palladium Catalyst for the Fluorination of Arylboronic Acids using Data Science Tools
ord-deolka-2025-pd-fluorination-arylboronic · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Automated stopped-flow library synthesis for rapid optimisation and machine learning directed experimentation
ord-avila-2022-stopped-flow-library-synthesis · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Generation of multimillion chemical space based on the parallel Groebke–Blackburn–Bienaymé reaction
ord-govor-2024-gbb-parallel-synthesis · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Accelerated exploration of heterogeneous CO2 hydrogenation catalysts by Bayesian-optimized high-throughput and automated experimentation
ord-ramirez-2024-co2-hydrogenation-hte · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Accelerating reaction generality and mechanistic insight through additive mapping
ord-prieto-kullmer-2022-additive-mapping-ni-photoredox · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Nanoscale synthesis and affinity ranking
ord-gesmundo-2018-nanoscale-synthesis-affinity · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Precipitation-first Synthesis and Deep Profiling of a 1,200-Member Acrylamide Library for Covalent Drug Discovery
ord-patil-2025-acrylamide-library · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Reaction screening in multiwell plates: high-throughput optimization of a Buchwald–Hartwig amination
ord-cook-2021-buchwald-hartwig-96-well · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Identifying opportunities for late-stage C-H alkylation with high-throughput experimentation and in silico reaction screening
ord-nippa-2023-minisci-late-stage-alkylation · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Robot-assisted mapping of chemical reaction hyperspaces and networks
ord-jia-2025-robotic-reaction-hyperspaces · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Predicting Three-Component Reaction Outcomes from 40k Miniaturized Reactant Combinations
ord-gotz-2025-three-component-40k · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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A Low-Yield Reaction Is Still a Result: A Study on Grignard Reagent Free Cobalt Catalyzed C(sp2)-H Arylation
ord-narayanan-2025-cobalt-ch-arylation-hte · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Deconvoluting Low Yield from Weak Potency in Direct-to-Biology Workflows with Machine Learning
ord-mccorkindale-2024-d2b-amide-coupling · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Enhancing High-Throughput Experimentation Liquid-Handling Capabilities via Strategic Hardware Development of the Mantis Liquid Handler
ord-golden-2025-mantis-liquid-handler-hte · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Bayesian Optimization over Multiple Experimental Fidelities Accelerates Automated Discovery of Drug Molecules
ord-mcdonald-2025-multifidelity-bo-automated-synthesis · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Roboticized AI-assisted microfluidic photocatalytic synthesis and screening up to 10,000 reactions per day
ord-lu-2024-microfluidic-photocatalysis-screening · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Efficient large-scale exploration of fragment hit progression by exploiting binding-site purification of actives (B-SPA) through combining multi-step array synthesis and HT crystallography.
ord-grosjean-2025-bspa-fragment-array-synthesis · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Preparation of 2-Heteroaryl-indolin-3-ones by Acid-Mediated Intramolecular Cyclization in Batch and Flow
ord-saglam-2025-indolin-3-one-doe · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Predict HER activity of untested element systems from composition and computation
her-model · OCx25: community research on Open Catalyst Experiments · Build a model that predicts the HER cathode potential at 50 mA/cm2 for element s…
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Reproduce the OCx24 baseline models, then re-run them on the 2025 data under the Campaign protocol
reproduce-ocx24-baselines · OCx25: community research on Open Catalyst Experiments · Reproduce the paper's HER (linear) and CO2RR (random forest) models and their LO…
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Human and mouse clearance: released-data model benchmark
human-mouse-clearance-expansionrx · Human and mouse clearance: released-data model benchmark · Reproduce and score a model on 2,282 publicly released molecules, with exact dat…
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Factors to Consider for Synthesis in 1536-Well Plates─An Amide Coupling Case Study for PROTAC Synthesis
ord-stevens-2025-protac-amide-1536-well · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Continuous collective analysis of chemical reactions
ord-hu-2024-nl-ade-ms-collective-analysis · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery
ord-wang-2023-d2b-ugi-e3-modulators · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Enabling High Throughput Kinetic Experimentation by Using Flow as a Differential Kinetic Technique
ord-lennon-2023-flow-differential-kinetics · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Production and evaluation of high-throughput reaction data from an automated chemical synthesis platform
ord-zhong-2025-autocsp-hte-screening · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Audit OCx25 data quality and reproducibility
audit-dataset · OCx25: community research on Open Catalyst Experiments · A data-quality audit of the 2025 release: replicate reproducibility by source an…
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Propose testable catalyst hypotheses absent from the OCx25 dataset
propose-candidates · OCx25: community research on Open Catalyst Experiments · A ranked shortlist of 5–20 candidate compositions absent from the bound dataset,…
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Deciphering complexity in Pd–catalyzed cross-couplings
ord-clarke-2024-pd-cross-coupling-complexity · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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ChemBeads-Enabled Photoredox High-Throughput Experimentation Platform to Improve C(sp2)–C(sp3) Decarboxylative Couplings
ord-gesmundo-2023-chembead-photoredox-hte · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Rhodium-catalysed connective synthesis of diverse reactive probes bearing S(VI) electrophilic warheads
ord-rice-2025-rh-carbenoid-s-vi-probes · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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High-Throughput 19F NMR Chiral Analysis for Screening and Directed Evolution of Imine Reductases
ord-song-2025-ired-19f-nmr-screening · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Predicting relative efficiency of amide bond formation using multivariate linear regression
ord-haas-2022-amide-coupling-kinetics · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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A self-optimised approach to synthesising DEHiBA for advanced nuclear reprocessing, exploiting the power of machine-learning
ord-shaw-2023-dehiba-flow-self-optimisation · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Exploring the chemical space of phenyl sulfide oxidation by automated optimization
ord-mueller-2023-phenyl-sulfide-oxidation · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Stereodivergent Construction of Decalin-Based Terpenoids
ord-barlock-2025-decalin-terpenoid-hte · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Aryl Amination Using Soluble Weak Base Enabled by a Water-Assisted Mechanism
ord-lau-2020-aryl-amination-weak-base · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Merging Directed C–H Activations with High-Throughput Experimentation: Development of Iridium-Catalyzed C–H Aminations Applicable to Late-Stage Functionalization
ord-weis-2022-ir-ch-amination-hte · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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A General, Multimetallic Cross-Ullmann Biheteroaryl Synthesis from Heteroaryl Halides and Heteroaryl Triflates
ord-kang-2021-cross-ullmann-biheteroaryl · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Miniaturised cross-coupling reactions: Solid dispensing approach for high-throughput screening
ord-radzilani-2025-solid-dispensing-cross-coupling · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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High-Throughput Discovery and Evaluation of a General Catalytic Method for N-Arylation of Weakly Nucleophilic Sulfonamides
ord-becica-2019-sulfonamide-n-arylation · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Automated multi-objective reaction optimisation: which algorithm should I use
ord-muller-2022-multiobjective-flow-optimisation · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Parallel and flow photoredox chemistry enabled by advanced temperature-controlled photoreactors
ord-borodin-2025-photoredox-photoreactors · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Accessing Diverse Azole Carboxylic Acid Building Blocks via Mild C–H Carboxylation: Parallel, One-Pot Amide Couplings and Machine-Learning-Guided Substrate Scope Design
ord-felten-2022-azole-ch-carboxylation-amide · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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Thinking Outside the Library: Cluster Synthesis of Diverse Molecules on a Single Robotic Platform
ord-le-vaillant-2025-robotic-cluster-synthesis · Open Reaction Database: dataset wishlist · Curate this paper's reaction data into a validated Open Reaction Database datase…
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1
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